Download Sirtuins (Proteins and Cell Regulation) by Riekelt H. Houtkooper PDF

By Riekelt H. Houtkooper

The sirtuin kinfolk of proteins (SIRT1-7) bought loads of recognition in recent times as they function metabolic sensors that keep watch over not just metabolism, but additionally getting older and lifespan law. As such, sirtuins are powerful ambitions for the remedy of age-related metabolic ailments, together with weight problems, diabetes, and melanoma. certainly, many learn teams in addition to pharmaceutical businesses stumbled on foodstuff elements and/or medicinal drugs that concentrate on the sirtuins and supply major overall healthiness advantages. This booklet makes a speciality of a number of facets of sirtuin biology, from simple biochemistry, through molecular functionality, to its position in (fighting) human disease.

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